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Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants
Most genetic association signals for type 2 diabetes risk are located in non-coding regions of the genome, hindering translation into molecular mechanisms. Physiological studies have shown a majority of disease-associated variants to exert their effects through pancreatic islet dysfunction. Systemat...
Tallennettuna:
| Julkaisussa: | Diabetes |
|---|---|
| Päätekijät: | , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402869/ https://ncbi.nlm.nih.gov/pubmed/27554474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db16-0361 |
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