N of 1 trials and the optimal individualisation of drug treatments: a systematic review protocol

BACKGROUND: Guidelines and evidence-based drug treatment recommendations are usually based on the results of clinical trials, which have limited generalisability in routine clinical settings due to their restrictive eligibility criteria. These trials are also conducted in ideal and rigorously contro...

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Bibliographic Details
Published in:Syst Rev
Main Authors: Demeyin, Weyinmi A., Frost, Julia, Ukoumunne, Obioha C., Briscoe, Simon, Britten, Nicky
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
Subjects:
Protocol
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402671/
https://ncbi.nlm.nih.gov/pubmed/28438226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13643-017-0479-6
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