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Neuroendocrine androgen action is a key extraovarian mediator in the development of polycystic ovary syndrome

Polycystic ovary syndrome (PCOS) is a complex hormonal disorder characterized by reproductive, endocrine, and metabolic abnormalities. As the origins of PCOS remain unknown, mechanism-based treatments are not feasible and current management relies on treatment of symptoms. Hyperandrogenism is the mo...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Caldwell, Aimee S. L., Edwards, Melissa C., Desai, Reena, Jimenez, Mark, Gilchrist, Robert B., Handelsman, David J., Walters, Kirsty A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402450/
https://ncbi.nlm.nih.gov/pubmed/28320971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616467114
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