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Oxoaporphine Metal Complexes (Co(II), Ni(II), Zn(II)) with High Antitumor Activity by Inducing Mitochondria-Mediated Apoptosis and S-phase Arrest in HepG2
Three new oxoaporphine Co(II), Ni(II) and Zn(II) complexes 1–3 have been synthesized and fully characterized. 1–3 have similar mononuclear structures with the metal and ligand ratio of 1:2. 1–3 exhibited higher cytotoxicity than the OD ligand and cisplatin against HepG2, T-24, BEL-7404, MGC80–3 and...
Tallennettuna:
Julkaisussa: | Sci Rep |
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Päätekijät: | , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Nature Publishing Group
2017
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402304/ https://ncbi.nlm.nih.gov/pubmed/28436418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46056 |
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