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Mammalian poly(A)-binding protein is a eukaryotic translation initiation factor, which acts via multiple mechanisms

Translation initiation is a multistep process involving several canonical translation factors, which assemble at the 5′-end of the mRNA to promote the recruitment of the ribosome. Although the 3′ poly(A) tail of eukaryotic mRNAs and its major bound protein, the poly(A)-binding protein (PABP), have b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kahvejian, Avak, Svitkin, Yuri V., Sukarieh, Rami, M'Boutchou, Marie-Noël, Sonenberg, Nahum
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC540229/
https://ncbi.nlm.nih.gov/pubmed/15630022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1262905
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