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Fasciola hepatica glycoconjugates immuneregulate dendritic cells through the Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin inducing T cell anergy

Dendritic cell-specific ICAM-3 grabbing non-integrin (DC-SIGN) expressed on a variety of DCs, is a C-type lectin receptor that recognizes glycans on a diverse range of pathogens, including parasites. The interaction of DC-SIGN with pathogens triggers specific signaling events that modulate DC-matura...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Rodríguez, Ernesto, Kalay, Hakan, Noya, Verónica, Brossard, Natalie, Giacomini, Cecilia, van Kooyk, Yvette, García-Vallejo, Juan J., Freire, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402274/
https://ncbi.nlm.nih.gov/pubmed/28436457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46748
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