Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper–Hollow Silica Nanoparticles

Combination chemotherapy has become the primary strategy against cancer multidrug resistance; however, accomplishing optimal pharmacokinetic delivery of multiple drugs is still challenging. Herein, we report a sequential combination drug delivery strategy exploiting a pH-triggerable and redox switch...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Palanikumar, L., Jeena, M. T., Kim, Kibeom, Yong Oh, Jun, Kim, Chaekyu, Park, Myoung-Hwan, Ryu, Ja-Hyoung
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402273/
https://ncbi.nlm.nih.gov/pubmed/28436438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46540
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