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Spatiotemporally and Sequentially-Controlled Drug Release from Polymer Gatekeeper–Hollow Silica Nanoparticles

Combination chemotherapy has become the primary strategy against cancer multidrug resistance; however, accomplishing optimal pharmacokinetic delivery of multiple drugs is still challenging. Herein, we report a sequential combination drug delivery strategy exploiting a pH-triggerable and redox switch...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Palanikumar, L., Jeena, M. T., Kim, Kibeom, Yong Oh, Jun, Kim, Chaekyu, Park, Myoung-Hwan, Ryu, Ja-Hyoung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402273/
https://ncbi.nlm.nih.gov/pubmed/28436438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46540
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