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Thermal stability, storage and release of proteins with tailored fit in silica

Biological substances based on proteins, including vaccines, antibodies, and enzymes, typically degrade at room temperature over time due to denaturation, as proteins unfold with loss of secondary and tertiary structure. Their storage and distribution therefore relies on a “cold chain” of continuous...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Yun-Chu, Smith, Tristan, Hicks, Robert H., Doekhie, Aswin, Koumanov, Francoise, Wells, Stephen A., Edler, Karen J., van den Elsen, Jean, Holman, Geoffrey D., Marchbank, Kevin J., Sartbaeva, Asel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5402271/
https://ncbi.nlm.nih.gov/pubmed/28436442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46568
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