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UBF-binding site arrays form pseudo-NORs and sequester the RNA polymerase I transcription machinery
Human ribosomal genes (rDNA) are located in nucleolar organizer regions (NORs) on the short arms of acrocentric chromosomes. Metaphase NORs that were transcriptionally active in the previous cell cycle appear as prominent chromosomal features termed secondary constrictions that are achromatic in chr...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC540225/ https://ncbi.nlm.nih.gov/pubmed/15598984 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310705 |
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