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Different configurational states of beta-amyloid and their distributions relative to plaques and tangles in Alzheimer disease.

Antibodies have been raised against synthetic peptides corresponding to different parts of the beta-amyloid sequence. These antibodies stain different kinds of amyloid distributions in the hippocampal formation in Alzheimer disease, suggesting the existence of different states of aggregation and/or...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Spillantini, M G, Goedert, M, Jakes, R, Klug, A
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1990
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54021/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2111023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3947
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