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The ST2/IL-33 Axis in Immune Cells during Inflammatory Diseases
Il1rl1 (also known as ST2) is a member of the IL-1 superfamily, and its only known ligand is IL-33. ST2 exists in two forms as splice variants: a soluble form (sST2), which acts as a decoy receptor, sequesters free IL-33, and does not signal, and a membrane-bound form (ST2), which activates the MyD8...
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| Udgivet i: | Front Immunol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5402045/ https://ncbi.nlm.nih.gov/pubmed/28484466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00475 |
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