Tolerability, pharmacokinetics and antiviral activity of rHSA/IFNα2a for the treatment of chronic hepatitis B infection

AIMS: A recombinant human serum albumin‐interferon alpha2a fusion protein (rHSA/IFNα2a) is expected to extend the half‐life of IFNα2a. This study aims to evaluate the tolerability, safety and efficacy of rHSA/IFNα2a. METHODS: This is an open, randomized, positive control, multiple‐dose ascending Pha...

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Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Ding, Yanhua, Lou, Jinfeng, Chen, Hong, Li, Xiaojiao, Wu, Min, Li, Cuiyun, Liu, Jingrui, Liu, Chengjiao, Li, Qingmei, Zhang, Hong, Niu, Junqi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5401974/
https://ncbi.nlm.nih.gov/pubmed/27862178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13184
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