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Antinucleosome Antibodies and Decreased Deoxyribonuclease Activity in Sera of Patients with Systemic Lupus Erythematosus

Nucleosomes are the dominant autoantigens in patients with systemic lupus erythematosus (SLE), and immune complexes involving nucleosomes are the major cause of tissue damage. The activity of DNase I, the enzyme responsible for nucleosome degradation, has been found to be decreased in patients with...

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Main Authors: Sallai, Krisztina, Nagy, Eszter, Derfalvy, Beata, Müzes, Györgyi, Gergely, Peter
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC540196/
https://ncbi.nlm.nih.gov/pubmed/15642985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CDLI.12.1.56-59.2005
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