Antinucleosome Antibodies and Decreased Deoxyribonuclease Activity in Sera of Patients with Systemic Lupus Erythematosus

Nucleosomes are the dominant autoantigens in patients with systemic lupus erythematosus (SLE), and immune complexes involving nucleosomes are the major cause of tissue damage. The activity of DNase I, the enzyme responsible for nucleosome degradation, has been found to be decreased in patients with...

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Vydáno v:	Clin Diagn Lab Immunol
Hlavní autoři:	Sallai, Krisztina, Nagy, Eszter, Derfalvy, Beata, Müzes, Györgyi, Gergely, Peter
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2005
Témata:	Vaccine Immunology and Clinical Trials
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC540196/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15642985/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/CDLI.12.1.56-59.2005
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