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Variation of the Polymorphic Region X of the Protein A Gene during Persistent Airway Infection of Cystic Fibrosis Patients Reflects Two Independent Mechanisms of Genetic Change in Staphylococcus aureus

Variation of the polymorphic region of the protein A gene (spa) was observed during long-term persistence of Staphylococcus aureus in the airways of 10 cystic fibrosis patients and occurred at a rate of one genetic change every 70 months. Independent mutational events were observed eight times in 14...

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Autors principals: Kahl, Barbara C., Mellmann, Alexander, Deiwick, Susanne, Peters, Georg, Harmsen, Dag
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC540147/
https://ncbi.nlm.nih.gov/pubmed/15635028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.43.1.502-505.2005
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