The Pseudomonas aeruginosa PrrF Small RNAs Regulate Iron Homeostasis during Acute Murine Lung Infection

Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that requires iron for virulence. Iron homeostasis is maintained in part by the PrrF1 and PrrF2 small RNAs (sRNAs), which block the expression of iron-containing proteins under iron-depleted conditions. The PrrF sRNAs also promote the...

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Detalles Bibliográficos
Publicado en:Infect Immun
Main Authors: Reinhart, Alexandria A., Nguyen, Angela T., Brewer, Luke K., Bevere, Justin, Jones, Jace W., Kane, Maureen A., Damron, F. Heath, Barbier, Mariette, Oglesby-Sherrouse, Amanda G.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
Assuntos:
Molecular Pathogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400841/
https://ncbi.nlm.nih.gov/pubmed/28289146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00764-16
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