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Functional assessment of a novel COL4A5 splice region variant and immunostaining of plucked hair follicles as an alternative method of diagnosis in X-linked Alport syndrome

INTRODUCTION: Many COL4A5 splice region variants have been described in patients with X-linked Alport syndrome, but few have been confirmed by functional analysis to actually cause defective splicing. We sought to demonstrate that a novel COL4A5 splice region variant in a family with Alport syndrome...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Pediatr Nephrol
Päätekijät: Malone, Andrew F., Funk, Steven D., Alhamad, Tarek, Miner, Jeffrey H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400701/
https://ncbi.nlm.nih.gov/pubmed/28013382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-016-3565-4
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