IL-6 secreted by cancer-associated fibroblasts promotes epithelial-mesenchymal transition and metastasis of gastric cancer via JAK2/STAT3 signaling pathway

Cancer-associated fibroblasts (CAFs), as the activated fibroblasts in tumor stroma, are important modifiers of tumor progression. However, the molecular mechanisms underlying the tumor-promoting properties of CAFs in gastric cancer remain unclear. Here, we show that CAFs isolated from gastric cancer...

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Publicado en:Oncotarget
Autores principales: Wu, Xiongyan, Tao, Pan, Zhou, Quan, Li, Jie, Yu, Zhenjia, Wang, Xiaofeng, Li, Jiaanfang, Li, Chen, Yan, Min, Zhu, Zhenggang, Liu, Bingya, Su, Liping
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400541/
https://ncbi.nlm.nih.gov/pubmed/28186964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15119
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