Inositol polyphosphate multikinase promotes Toll-like receptor–induced inflammation by stabilizing TRAF6

Toll-like receptor (TLR) signaling is tightly controlled to protect hosts from microorganisms while simultaneously preventing uncontrolled immune responses. Tumor necrosis factor receptor–associated factor 6 (TRAF6) is a critical mediator of TLR signaling, but the precise mechanism of how TRAF6 prot...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Kim, Eunha, Beon, Jiyoon, Lee, Seulgi, Park, Seung Ju, Ahn, Hyoungjoon, Kim, Min Gyu, Park, Jeong Eun, Kim, Wooseob, Yuk, Jae-Min, Kang, Suk-Jo, Lee, Seung-Hyo, Jo, Eun-Kyeong, Seong, Rho Hyun, Kim, Seyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400429/
https://ncbi.nlm.nih.gov/pubmed/28439546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1602296
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