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Modulation the alternative splicing of GLA (IVS4+919G>A) in Fabry disease

While a base substitution in intron 4 of GLA (IVS4+919G>A) that causes aberrant alternative splicing resulting in Fabry disease has been reported, its molecular mechanism remains unclear. Here we reported that upon IVS4+919G>A transversion, H3K36me3 was enriched across the alternatively splice...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Chang, Wen-Hsin, Niu, Dau-Ming, Lu, Chi-Yu, Lin, Shyr-Yi, Liu, Ta-Chih, Chang, Jan-Gowth
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400244/
https://ncbi.nlm.nih.gov/pubmed/28430823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175929
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