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An unmodified wobble uridine in tRNAs specific for Glutamine, Lysine, and Glutamic acid from Salmonella enterica Serovar Typhimurium results in nonviability—Due to increased missense errors?

In the wobble position of tRNAs specific for Gln, Lys, and Glu a universally conserved 5-methylene-2-thiouridine derivative (xm(5)s(2)U34, x denotes any of several chemical substituents and 34 denotes the wobble position) is present, which is 5-(carboxy)methylaminomethyl-2-thiouridine ((c)mnm(5)s(2)...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Nilsson, Kristina, Jäger, Gunilla, Björk, Glenn R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400242/
https://ncbi.nlm.nih.gov/pubmed/28430781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175092
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