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An unmodified wobble uridine in tRNAs specific for Glutamine, Lysine, and Glutamic acid from Salmonella enterica Serovar Typhimurium results in nonviability—Due to increased missense errors?

In the wobble position of tRNAs specific for Gln, Lys, and Glu a universally conserved 5-methylene-2-thiouridine derivative (xm(5)s(2)U34, x denotes any of several chemical substituents and 34 denotes the wobble position) is present, which is 5-(carboxy)methylaminomethyl-2-thiouridine ((c)mnm(5)s(2)...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Nilsson, Kristina, Jäger, Gunilla, Björk, Glenn R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400242/
https://ncbi.nlm.nih.gov/pubmed/28430781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175092
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