Longitudinal diffusion changes in prodromal and early HD: Evidence of white‐matter tract deterioration

INTRODUCTION: Huntington's disease (HD) is a genetic neurodegenerative disorder that primarily affects striatal neurons. Striatal volume loss is present years before clinical diagnosis; however, white matter degradation may also occur prior to diagnosis. Diffusion‐weighted imaging (DWI) can mea...

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Vydáno v:Hum Brain Mapp
Hlavní autoři: Shaffer, Joseph J., Ghayoor, Ali, Long, Jeffrey D., Kim, Regina Eun‐Young, Lourens, Spencer, O'Donnell, Lauren J., Westin, Carl‐Fredrik, Rathi, Yogesh, Magnotta, Vincent, Paulsen, Jane S., Johnson, Hans J.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400101/
https://ncbi.nlm.nih.gov/pubmed/28045213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hbm.23465
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