Localized and Controlled Delivery of Nitric Oxide to the Conventional Outflow Pathway via Enzyme Biocatalysis: Toward Therapy for Glaucoma

Nitric oxide (NO) is able to lower intraocular pressure (IOP); however, its therapeutic effects on outflow physiology are location‐ and dose‐dependent. A NO delivery platform that directly targets the resistance‐generating region of the conventional outflow pathway and locally liberates a controlled...

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Detalhes bibliográficos
Publicado no:Adv Mater
Main Authors: Chandrawati, Rona, Chang, Jason Y. H., Reina‐Torres, Ester, Jumeaux, Coline, Sherwood, Joseph M., Stamer, W. Daniel, Zelikin, Alexander N., Overby, Darryl R., Stevens, Molly M.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5400071/
https://ncbi.nlm.nih.gov/pubmed/28221702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201604932
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