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Transmission fitness of drug-resistant HIV revealed in a surveillance system transmission network

Test-and-treat programs are central to the global control of HIV, but transmitted drug resistance threatens the effectiveness of these programs. HIV mutations conferring resistance to antiretroviral drugs reduce replicative fitness in vitro, but their effect on propagation in vivo is less understood...

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Vydáno v:Virus Evol
Hlavní autoři: Wertheim, Joel O., Oster, Alexandra M., Johnson, Jeffrey A., Switzer, William M., Saduvala, Neeraja, Hernandez, Angela L., Hall, H. Irene, Heneine, Walid
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399924/
https://ncbi.nlm.nih.gov/pubmed/28458918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ve/vex008
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