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Epigenomics of human CD8 T cell differentiation and aging
The efficacy of the adaptive immune response declines dramatically with age, but the cell-intrinsic mechanisms driving immune aging in humans remain poorly understood. Immune aging is characterized by a loss of self-renewing naïve cells and the accumulation of differentiated but dysfunctional cells...
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| Publicado en: | Sci Immunol |
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| Autores principales: | , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399889/ https://ncbi.nlm.nih.gov/pubmed/28439570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aag0192 |
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