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Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung

BACKGROUND: Aldehyde dehydrogenases (ALDHs) play a major role in detoxification of aldehydes. High expression of ALDHs is a marker for stem cells of many organs including the lungs. A common polymorphism in ALDH2 gene (ALDH2*2) results in inactivation of the enzyme and is associated with alcohol flu...

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Kuroda, Aoi, Hegab, Ahmed E., Jingtao, Gao, Yamashita, Shuji, Hizawa, Nobuyuki, Sakamoto, Tohru, Yamada, Hideyasu, Suzuki, Satoshi, Ishii, Makoto, Namkoong, Ho, Asakura, Takanori, Ozaki, Mari, Yasuda, Hiroyuki, Hamamoto, Junko, Kagawa, Shizuko, Soejima, Kenzo, Betsuyaku, Tomoko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399815/
https://ncbi.nlm.nih.gov/pubmed/28431562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0554-5
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