Depressed basal hypothalamic neuronal activity in type-1 diabetic mice is correlated with proinflammatory secretion of HMBG1

We recently found indicators of hypothalamic inflammation and neurodegeneration linked to the loss of neuroprotective factors including insulin-like growth factor (IGF-1) and IGF binding protein-2 (IGFBP-3) in mice made diabetic using streptozotocin (STZ). In the current work, a genetic model of typ...

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Bibliografske podrobnosti
izdano v:Neurosci Lett
Main Authors: Thinschmidt, Jeffrey S., Colon Perez, Luis M., Febo, Marcelo, Caballero, Sergio, King, Michael A., White, Fletcher A., Grant, Maria B.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399679/
https://ncbi.nlm.nih.gov/pubmed/26777426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2016.01.014
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