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Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation

Folate supplementation prevents up to 70% of neural tube defects (NTDs), which result from a failure of neural tube closure during embryogenesis. The elucidation of the mechanisms underlying folate action has been challenging. This study introduces Xenopus laevis as a model to determine the cellular...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Balashova, Olga A., Visina, Olesya, Borodinsky, Laura N.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399658/
https://ncbi.nlm.nih.gov/pubmed/28255006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137315
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