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Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation
Folate supplementation prevents up to 70% of neural tube defects (NTDs), which result from a failure of neural tube closure during embryogenesis. The elucidation of the mechanisms underlying folate action has been challenging. This study introduces Xenopus laevis as a model to determine the cellular...
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Publicado no: | Development |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Company of Biologists Ltd
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399658/ https://ncbi.nlm.nih.gov/pubmed/28255006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.137315 |
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