Clinical efficacy of omalizumab in chronic spontaneous urticaria is associated with a reduction of FcεRI-positive cells in the skin

Background. Treatment with omalizumab, a humanized recombinant monoclonal anti-IgE antibody, results in clinical efficacy in patients with Chronic Spontaneous Urticaria (CSU). The mechanism of action of omalizumab in CSU has not been elucidated in detail. Objectives. To determine the effects of omal...

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Udgivet i:Theranostics
Main Authors: Metz, Martin, Staubach, Petra, Bauer, Andrea, Brehler, Randolf, Gericke, Janine, Kangas, Michael, Ashton-Chess, Joanna, Jarvis, Philip, Georgiou, Panayiotis, Canvin, Janice, Hillenbrand, Rainer, Erpenbeck, Veit J., Maurer, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: Ivyspring International Publisher 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399592/
https://ncbi.nlm.nih.gov/pubmed/28435464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.18304
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