Allergic Asthma is Distinguished by Sensitivity of Allergen-Specific CD4(+) T Cells and Airway Structural Cells to Type 2 Inflammation

Despite systemic sensitization, not all allergic individuals develop asthma symptoms upon airborne allergen exposure. Determination of the factors that lead to the asthma phenotype in allergic individuals could guide treatment and identify novel therapeutic targets. In this study, we utilized segmen...

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Publicat a:Sci Transl Med
Autors principals: Cho, Josalyn L., Ling, Morris F., Adams, David C., Faustino, Lucas, Islam, Sabina A., Afshar, Roshi, Griffith, Jason W., Harris, Robert S., Ng, Aylwin, Radicioni, Giorgia, Ford, Amina A., Han, Andre K., Xavier, Ramnik, Kwok, William W., Boucher, Richard, Moon, James J., Hamilos, Daniel L., Kesimer, Mehmet, Suter, Melissa J., Medoff, Benjamin D., Luster, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399547/
https://ncbi.nlm.nih.gov/pubmed/27708065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aag1370
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