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Role of Endothelin-1 in a Syndrome of Myelofibrosis and Osteosclerosis

CONTEXT: Primary myelofibrosis is one of the chronic myeloproliferative disorders characterized by bone marrow fibrosis associated with extramedullary hematopoiesis and osteosclerosis. Endothelin-1 (ET1) is a potent vasoconstrictor that is also a key mediator of osteoblastic bone metastases by stimu...

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Bibliografische gegevens
Gepubliceerd in:J Clin Endocrinol Metab
Hoofdauteurs: Yachoui, Ralph, Kristianto, Jasmin, Sitwala, Kajal, Blank, Robert D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399504/
https://ncbi.nlm.nih.gov/pubmed/26358171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2015-2729
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