Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by (1)H NMR spectroscopy

Hyperpolarization enhances the intensity of the NMR signals of a molecule, whose in vivo metabolic fate can be monitored by MRI with higher sensitivity. SABRE is a hyperpolarization technique that could potentially be used to image nitric oxide (NO) production in vivo. This would be very important,...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem
Main Authors: Fernandez Diaz-Rullo, Fernando, Zamberlan, Francesco, Mewis, Ryan E., Fekete, Marianna, Broche, Lionel, Cheyne, Lesley A., Dall'Angelo, Sergio, Duckett, Simon B., Dawson, Dana, Zanda, Matteo
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399308/
https://ncbi.nlm.nih.gov/pubmed/28365086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.03.041
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