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A Functional Interleukin-18 Haplotype Predicts Depression and Anxiety through Increased Threat-Related Amygdala Reactivity in Women but Not Men

Common functional polymorphisms in the gene encoding interleukin-18 (IL18), a cytokine belonging to the IL-1 superfamily that can induce synthesis of several other cytokines, have been associated with major depressive episodes following the experience of stressful life events. The neural mechanisms...

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Publicado en:Neuropsychopharmacology
Main Authors: Swartz, Johnna R, Prather, Aric A, Di Iorio, Christina R, Bogdan, Ryan, Hariri, Ahmad R
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399226/
https://ncbi.nlm.nih.gov/pubmed/27430614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.129
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