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The anticancer effect of chaetocin is enhanced by inhibition of autophagy

Chaetocin is a fungal metabolite that possesses a potent antiproliferative activity in solid tumors by inducing cell death. Although recent studies have extended the role of chaetocin in tumors, the underlying molecular mechanisms such as the downstream cascade that induces cell death has not clearl...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Jung, H-J, Seo, I, Casciello, F, Jacquelin, S, Lane, S W, Suh, S-Il, Suh, M-H, Lee, J S, Baek, W-K
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5399187/
https://ncbi.nlm.nih.gov/pubmed/26890137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.15
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