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A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin
Hydrogen sulfide is a critical signaling molecule, but high concentrations cause cellular toxicity. A four-enzyme pathway in the mitochondrion detoxifies H(2)S by converting it to thiosulfate and sulfate. Recent studies have shown that globins like hemoglobin and myoglobin can also oxidize H(2)S to...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5399104/ https://ncbi.nlm.nih.gov/pubmed/28246171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.770370 |
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