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Changes in the sialylation and sulfation of secreted thyrotropin in congenital hypothyroidism.

We have examined the oligosaccharide structure of secreted thyrotropin (TSH) in perinatal and mature rats with congenital primary hypothyroidism. Rat pituitaries from euthyroid control animals and those rendered hypothyroid by methimazole treatment were incubated with [3H]glucosamine in vitro. Secre...

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Detalhes bibliográficos
Main Authors: Gyves, P W, Gesundheit, N, Thotakura, N R, Stannard, B S, DeCherney, G S, Weintraub, B D
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC53989/
https://ncbi.nlm.nih.gov/pubmed/1692623
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