Mice expressing a “hyper-sensitive” form of the CB(1) cannabinoid receptor (CB(1)) show modestly enhanced alcohol preference and consumption

We recently characterized S426A/S430A mutant mice expressing a desensitization-resistant form of the CB(1) receptor. These mice display an enhanced response to endocannabinoids and ∆(9)-THC. In this study, S426A/S430A mutants were used as a novel model to test whether ethanol consumption, morphine d...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Marcus, David J., Henderson-Redmond, Angela N., Gonek, Maciej, Zee, Michael L., Farnsworth, Jill C., Amin, Randa A., Andrews, Mary-Jeanette, Davis, Brian J., Mackie, Ken, Morgan, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398885/
https://ncbi.nlm.nih.gov/pubmed/28426670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174826
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