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Protein synthesis during acquisition of long-term facilitation is needed for the persistent loss of regulatory subunits of the Aplysia cAMP-dependent protein kinase.

Depending on the number or the length of exposure, application of serotonin can produce either short-term or long-term presynaptic facilitation of Aplysia sensory-to-motor synapses. The cAMP-dependent protein kinase, a heterodimer of two regulatory and two catalytic subunits, has been shown to becom...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bergold, P J, Sweatt, J D, Winicov, I, Weiss, K R, Kandel, E R, Schwartz, J H
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1990
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53988/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1692622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.10.3788
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