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Uncovering the molecular and physiological processes of anticancer leads binding human serum albumin: A physical insight into drug efficacy

Human serum albumin (HSA) has its ability to bind drug molecules and influence their efficacies. Although anticancer leads NSC48693 and NSC290956 functioned at the same mechanism, the drug efficacies were obviously distinct. To gain insight into the distinct drug efficacy, the molecular and physiolo...

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Bibliographic Details
Published in:PLoS One
Main Authors: Liu, Chuanbo, Liu, Zuojia, Wang, Jin
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398698/
https://ncbi.nlm.nih.gov/pubmed/28426740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0176208
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