cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells

CD34(+) hematopoietic progenitor cells have been shown to be susceptible to HIV-1 infection, possibly due to a low-level expression of CXCR4, a coreceptor for HIV-1 entry. Given these observations, we have explored the impact of forskolin on cell surface expression of CXCR4 in a cell line model (TF-...

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Detalhes bibliográficos
Publicado no:Clin Med Insights Pathol
Main Authors: Banerjee, Anupam, Li, Luna, Pirrone, Vanessa, Krebs, Fred C, Wigdahl, Brian, Nonnemacher, Michael R
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398651/
https://ncbi.nlm.nih.gov/pubmed/28469516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1179555717694535
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