Anti-IL-20 monoclonal antibody inhibited inflammation and protected against cartilage destruction in murine models of osteoarthritis

Osteoarthritis (OA) is a degenerative joint disease characterized by progressive destruction of articular cartilage. Interleukin (IL)-20 is a proinflammatory cytokine involved in the pathogenesis of rheumatoid arthritis. We investigated the role of IL-20 in OA and evaluated whether anti-IL-20 antibo...

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Vydáno v:PLoS One
Hlavní autoři: Hsu, Yu-Hsiang, Yang, Ya-Yu, Huwang, Man-Hsiang, Weng, Yun-Han, Jou, I-Ming, Wu, Po-Tin, Lin, Tain-Yu, Wu, Li-Wha, Chang, Ming-Shi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398531/
https://ncbi.nlm.nih.gov/pubmed/28426699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0175802
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