High-Fat Feeding-Induced Hyperinsulinemia Increases Cardiac Glucose Uptake and Mitochondrial Function Despite Peripheral Insulin Resistance

In obesity, reduced cardiac glucose uptake and mitochondrial abnormalities are putative causes of cardiac dysfunction. However, high-fat diet (HFD) does not consistently induce cardiac insulin resistance and mitochondrial damage, and recent studies suggest HFD may be cardioprotective. To determine c...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Gupte, Anisha A., Minze, Laurie J., Reyes, Maricela, Ren, Yuelan, Wang, Xukui, Brunner, Gerd, Ghosn, Mohamad, Cordero-Reyes, Andrea M., Ding, Karen, Pratico, Domenico, Morrisett, Joel, Shi, Zheng-Zheng, Hamilton, Dale J., Lyon, Christopher J., Hsueh, Willa A.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2013
Assuntos:
Energy Balance-Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398492/
https://ncbi.nlm.nih.gov/pubmed/23709089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-2272
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