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Vitamin C conjugates of genotoxic lipid peroxidation products: Structural characterization and detection in human plasma

α,β-Unsaturated aldehydes such as 4-hydroxy-2-nonenal (HNE) and other electrophilic lipid peroxidation (LPO) products may contribute to the pathogenesis of cancer, cardiovascular diseases, and other age-related diseases by cytotoxic, genotoxic, and proinflammatory mechanisms. The notion that vitamin...

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Detalhes bibliográficos
Main Authors: Sowell, John, Frei, Balz, Stevens, Jan F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC539811/
https://ncbi.nlm.nih.gov/pubmed/15608056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408433102
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