Alcohol Induces Cellular Senescence and Impairs Osteogenic Potential in Bone Marrow-Derived Mesenchymal Stem Cells

AIMS: Chronic and excessive alcohol consumption is a high-risk factor for osteoporosis. Bone marrow-derived mesenchymal stem cells (BM-MSCs) play an important role in bone formation; however, they are vulnerable to ethanol (EtOH). The purpose of this research was to investigate whether EtOH could in...

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Veröffentlicht in:Alcohol Alcohol
Hauptverfasser: Chen, Xi, Li, Mao, Yan, Jinku, Liu, Tao, Pan, Guoqing, Yang, Huilin, Pei, Ming, He, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397879/
https://ncbi.nlm.nih.gov/pubmed/28339869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agx006
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