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Revealing Hidden Conformational Space of LOV Protein VIVID Through Rigid Residue Scan Simulations
VIVID(VVD) protein is a Light-Oxygen-Voltage(LOV) domain in circadian clock system. Upon blue light activation, a covalent bond is formed between VVD residue Cys108 and its cofactor flavin adenine dinucleotide(FAD), and prompts VVD switching from Dark state to Light state with significant conformati...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5397860/ https://ncbi.nlm.nih.gov/pubmed/28425502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep46626 |
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