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Isolation of cellular promoters by using a retrovirus promoter trap.

A retrovirus vector has been used to isolate transcriptional promoters from mammalian cells. The virus contains a selectable gene encoding histidinol dehydrogenase (his) in the U3 region of the 3' long terminal repeat (LTR). When the virus is passaged, duplication of LTRs places his sequences j...

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Autores principales: von Melchner, H, Reddy, S, Ruley, H E
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC53977/
https://ncbi.nlm.nih.gov/pubmed/2339116
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