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Caveolin 1 and G-Protein–Coupled Receptor Kinase-2 Coregulate Endothelial Nitric Oxide Synthase Activity in Sinusoidal Endothelial Cells

Liver injury leads to a vasculopathy in which post-translational modifications of endothelial nitric oxide synthase (eNOS) lead to impaired nitric oxide synthesis. We hypothesized that caveolin 1 (CAV1), a well-known eNOS interactor, regulates eNOS activity in sinusoidal endothelial cells (SECs) via...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Liu, Songling, Premont, Richard T., Singh, Shweta, Rockey, Don C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397668/
https://ncbi.nlm.nih.gov/pubmed/28162981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2016.11.017
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