Ovarian aging and the activation of the primordial follicle reserve in the long-lived Ames dwarf and the short-lived bGH transgenic mice

The aim of this study was to evaluate the effect of growth hormone (GH) in the maintenance of the ovarian primordial follicle reserve. Ovaries from 16 mo old GH-deficient Ames Dwarf (df/df) and Normal (N/df) mice were used. A subgroup of df/df and N mice received GH or saline injections for six week...

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Publicado en:Mol Cell Endocrinol
Autores principales: Saccon, Tatiana D., Moreira, Fabiana, Cruz, Luis A., Mondadori, Rafael G., Fang, Yimin, Barros, Carlos C., Spinel, L., Bartke, A., Masternak, Michal M., Schneider, A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397383/
https://ncbi.nlm.nih.gov/pubmed/27771355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2016.10.015
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