MR1 Restricted Mucosal-Associated Invariant T (MAIT) Cells Respond to Mycobacterial Vaccination and Infection in Nonhuman Primates

Studies on mucosal-associated invariant T cells (MAITs) in nonhuman primates (NHP), a physiologically relevant model of human immunity, are handicapped due to a lack of macaque MAIT-specific reagents. Here we show that while MR1 ligand-contact residues are conserved between human and multiple NHP sp...

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Pubblicato in:Mucosal Immunol
Autori principali: Greene, Justin M., Dash, Pradyot, Roy, Sobhan, McMurtrey, Curtis, Awad, Walid, Reed, Jason S., Hammond, Katherine B., Abdulhaqq, Shaheed, Wu, Helen L., Burwitz, Benjamin J., Roth, Benjamin F., Morrow, David W., Ford, Julia C., Xu, Guangwu, Bae, Joseph Y., Crank, Hugh, Legasse, Alfred W., Dang, Thurston H., Greenaway, Hui Yee, Kurniawan, Monica, Gold, Marielle C., Harriff, Melanie J., Lewinsohn, Deborah A., Park, Byung S., Axthelm, Michael K., Stanton, Jeffrey J., Hansen, Scott G., Picker, Louis J., Venturi, Vanessa, Hildebrand, William, Thomas, Paul G., Lewinsohn, David M., Adams, Erin J., Sacha, Jonah B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397382/
https://ncbi.nlm.nih.gov/pubmed/27759023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2016.91
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