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Transplanted Human Glial-Restricted Progenitors Can Rescue the Survival of Dysmyelinated Mice Independent of the Production of Mature, Compact Myelin

The therapeutic effect of glial progenitor transplantation in diseases of dysmyelination is currently attributed to the formation of new myelin. Using magnetic resonance imaging (MRI), we show that the therapeutic outcome in dysmyelinated shiverer mice is dependent on the extent of cell migration bu...

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Detalhes bibliográficos
Publicado no:Exp Neurol
Main Authors: Lyczek, Agatha, Arnold, Antje, Zhang, Jiangyang, Campanelli, James T., Janowski, Miroslaw, Bulte, Jeff W. M., Walczak, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397299/
https://ncbi.nlm.nih.gov/pubmed/28163160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2017.02.005
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