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Modeling fructose-load-induced hepatic de-novo lipogenesis by model simplification

Hepatic de-novo lipogenesis is a metabolic process implemented in the pathogenesis of type 2 diabetes. Clinically, the rate of this process can be ascertained by use of labeled acetate and stimulation by fructose administration. A systems pharmacology model of this process is desirable because it fa...

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Detalhes bibliográficos
Publicado no:Gene Regul Syst Bio
Main Authors: Allen, Richard J, Musante, Cynthia J
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5397296/
https://ncbi.nlm.nih.gov/pubmed/28469410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1177625017690133
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